For twenty years, we have been leading the animal welfare industry by investing in people and communities to end the cycle of animal homelessness. By building capacity for animal advocates in our own neighborhood, we increase animal well-being across the East Side Pet District and beyond! We are proudly located in East St. Louis, joining an already robust community of pet lovers. By removing barriers to foster and adoption, and providing an infusion of resources such as affordable, quality veterinary care and pet supplies – we unleash the power of partnership!
Want no tricks this Halloween, just happy healthy pets?
Donate to Gateway Pet Guardians for the first ever Great Fix Fundraiser with 1:1 Monster Match, October 28 – 30!
We want to raise lucky number $13,000 to help prevent pet homelessness in the East Side Pet District!
The Great Fix Fundraiser 1:1 Monster Match was made possible thanks to an anonymous donor, who gave in memory of her beloved pup, Princess Sophie. Princess Sophie saved lives because she was spayed.
Rescuing Animals
Community outreach
Spay & Neuter
Healthy Pets
Keeping Pets and People Together. This philosophy guided us to open the largest Pet Resource Center in the region (54,000 square feet) that includes an affordable veterinary clinic, pet supply retail store and grooming spa. For much of our building’s life, it was a school – Miles Davis Elementary.
Prior to our purchase in 2019, it stood vacant in an area with limited pet resources available. Today, it provides a lifesaving operation for animals in need and a reliable destination for community members to care for their pets, including access to a free pet food pantry and free spay/neuter program.




